SYNTHESIS, COMPUTER AIDED SCREENING AND PHARMACOLOGICAL EVALUATION OF 2/3-SUBSTITUTED-6(4-METHYLPHENYL)-4,5-DIHYDROPYRIDAZIN3(2H)-ONES, AND PYRIDAZINE SUBSTITUTED TRIAZINE

SYNTHESIS, COMPUTER AIDED SCREENING AND PHARMACOLOGICAL EVALUATION OF 2/3-SUBSTITUTED-6(4-METHYLPHENYL)-4,5-DIHYDROPYRIDAZIN3(2H)-ONES, AND PYRIDAZINE SUBSTITUTED TRIAZINE

The present research work involved synthesis of some novel pyridazine derivatives and evaluation of their analgesic and anti-inflammatory activities in experimental animals to obtain safer non-steroidal anti-inflammatory drugs (NSAIDs). Friedal craft acylation reaction of succinic anhydride with tol...

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Bibliographic Details
Main Authors:	Asif Husain, Sukhbir Lal Khokra, Sonakshi Seth, Shama S Garg, Pawan Kaushik, Aftab Ahmad, Shah Alam Khan
Format:	Article
Language:	English
Published:	Universitas Gadjah Mada 2015-12-01
Series:	Indonesian Journal of Pharmacy
Subjects:	Pyridazinone Hydrazine derivatives Chloropyridazine Triazin-2-imine

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