The PTK7-related transmembrane proteins off-track and off-track 2 are co-receptors for Drosophila Wnt2 required for male fertility.

Wnt proteins regulate many developmental processes and are required for tissue homeostasis in adult animals. The cellular responses to Wnts are manifold and are determined by the respective Wnt ligand and its specific receptor complex in the plasma membrane. Wnt receptor complexes contain a member o...

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Bibliographic Details
Main Authors: Karen Linnemannstöns, Caroline Ripp, Mona Honemann-Capito, Katja Brechtel-Curth, Marie Hedderich, Andreas Wodarz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4091708?pdf=render