Overexpression of lung resistance-related protein and P-glycoprotein and response to induction chemotherapy in acute myelogenous leukemia

Lung resistance-related protein (LRP) and P-glycoprotein (P-gp) are associated with multidrug resistance. P-gp overexpression reduces intracellular anticancer drug concentrations and is correlated with low remission rates. However, whether the presence of LRP influences the response to induction che...

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Bibliographic Details
Main Authors: Kazue Tsuji, Yan-Hua Wang, Minoko Takanashi, Tsuyoshi Odajima, Gabriel A. Lee, Hiroki Sugimori, Toshiko Motoji
Format: Article
Language:English
Published: PAGEPress Publications 2012-10-01
Series:Hematology Reports
Subjects:
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/4117