Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice

Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice

Previous studies demonstrated that L-Fabp KO mice are more susceptible to lithogenic diet (LD)-induced gallstones because of altered hepatic cholesterol metabolism and increased canalicular cholesterol secretion. Other studies demonstrated that liver-specific deletion of microsomal triglyceride tran...

Full description

Bibliographic Details
Main Authors: Yan Xie, Ho Yee Joyce Fung, Elizabeth P. Newberry, Susan Kennedy, Jianyang Luo, Rosanne M. Crooke, Mark J. Graham, Nicholas O. Davidson
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Lipid Research
Subjects:
canalicular cholesterol
bile acid
phospholipid
ATP binding cassette transporter
hepatic cholesterol metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520376872

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520376872

Similar Items