The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.

The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.

Current iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities in...

Full description

Bibliographic Details
Main Authors: Neima Briggs, Jill Weatherhead, K Jagannadha Sastry, Peter J Hotez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5025185?pdf=render
id doaj-fa9aef040ed64607a2f3066b8ec6296a
record_format Article
spelling doaj-fa9aef040ed64607a2f3066b8ec6296a2020-11-25T02:42:37ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352016-09-01109e000494410.1371/journal.pntd.0004944The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.Neima BriggsJill WeatherheadK Jagannadha SastryPeter J HotezCurrent iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities include evidence of causal associations between helminth infections and asthma or inflammatory bowel disease as well as the fact that helminth infections remain widespread in the United States, especially among populations at greatest risk for inflammatory and autoimmune diseases.http://europepmc.org/articles/PMC5025185?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Neima Briggs
Jill Weatherhead
K Jagannadha Sastry
Peter J Hotez
spellingShingle Neima Briggs
Jill Weatherhead
K Jagannadha Sastry
Peter J Hotez
The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
PLoS Neglected Tropical Diseases
author_facet Neima Briggs
Jill Weatherhead
K Jagannadha Sastry
Peter J Hotez
author_sort Neima Briggs
title The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
title_short The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
title_full The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
title_fullStr The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
title_full_unstemmed The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections.
title_sort hygiene hypothesis and its inconvenient truths about helminth infections.
publisher Public Library of Science (PLoS)
series PLoS Neglected Tropical Diseases
issn 1935-2727
1935-2735
publishDate 2016-09-01
description Current iterations of the hygiene hypothesis suggest an adaptive role for helminth parasites in shaping the proper maturation of the immune system. However, aspects of this hypothesis are based on assumptions that may not fully account for realities about human helminth infections. Such realities include evidence of causal associations between helminth infections and asthma or inflammatory bowel disease as well as the fact that helminth infections remain widespread in the United States, especially among populations at greatest risk for inflammatory and autoimmune diseases.
url http://europepmc.org/articles/PMC5025185?pdf=render
work_keys_str_mv AT neimabriggs thehygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT jillweatherhead thehygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT kjagannadhasastry thehygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT peterjhotez thehygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT neimabriggs hygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT jillweatherhead hygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT kjagannadhasastry hygienehypothesisanditsinconvenienttruthsabouthelminthinfections
AT peterjhotez hygienehypothesisanditsinconvenienttruthsabouthelminthinfections
_version_ 1724772619612323840

Similar Items