Investigate pathogenic mechanism of TXNDC5 in rheumatoid arthritis.

Investigate pathogenic mechanism of TXNDC5 in rheumatoid arthritis.

Hypoxia stimulates synovial hypoperfusion in rheumatoid arthritis (RA). TXNDC5 stimulates cellular proliferation in hypoxic conditions. We previously detected increased TXNDC5 expression in synovial tissues and blood from RA patients and demonstrated that the gene encoding TXNDC5 increased RA risk....

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Bibliographic Details
Main Authors: Lin Wang, Yabing Zheng, Hengwei Xu, Xinfeng Yan, Xiaotian Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3541148?pdf=render

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