Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy

A 22‑year‑old female presented with bilateral, progressive diminution of vision. Slit‑lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad‑based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM),...

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Main Authors: Parul Ichhpujani, Sushmita Kaushik, Amit Gupta, Surinder S Pandav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=528;epage=529;aulast=Ichhpujani
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spelling doaj-fa919aa818b84e13bdc1656181dae7622020-11-25T02:06:01ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-0168352852910.4103/ijo.IJO_1123_19Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopyParul IchhpujaniSushmita KaushikAmit GuptaSurinder S PandavA 22‑year‑old female presented with bilateral, progressive diminution of vision. Slit‑lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad‑based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM), a membrane extending from corneal endothelium to anterior iris surface causing traction was seen. Confocal microscopy showed an "epithelium‑like" transformation of the corneal endothelium. This case demonstrates a bilateral Chandler variant of the iridocorneal endothelial (ICE) syndrome where the diagnosis of Chandler′s disease was confirmed by confocal microscopy, after the mechanism of secondary angle closure was demonstrated by the UBM.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=528;epage=529;aulast=Ichhpujanichandler's syndromeconfocal microscopyiridocorneal endothelial cellsultrasound biomicroscopy
collection DOAJ
language English
format Article
sources DOAJ
author Parul Ichhpujani
Sushmita Kaushik
Amit Gupta
Surinder S Pandav
spellingShingle Parul Ichhpujani
Sushmita Kaushik
Amit Gupta
Surinder S Pandav
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
Indian Journal of Ophthalmology
chandler's syndrome
confocal microscopy
iridocorneal endothelial cells
ultrasound biomicroscopy
author_facet Parul Ichhpujani
Sushmita Kaushik
Amit Gupta
Surinder S Pandav
author_sort Parul Ichhpujani
title Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_short Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_full Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_fullStr Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_full_unstemmed Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
title_sort bilateral chandler's syndrome: uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
publisher Wolters Kluwer Medknow Publications
series Indian Journal of Ophthalmology
issn 0301-4738
1998-3689
publishDate 2020-01-01
description A 22‑year‑old female presented with bilateral, progressive diminution of vision. Slit‑lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad‑based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM), a membrane extending from corneal endothelium to anterior iris surface causing traction was seen. Confocal microscopy showed an "epithelium‑like" transformation of the corneal endothelium. This case demonstrates a bilateral Chandler variant of the iridocorneal endothelial (ICE) syndrome where the diagnosis of Chandler′s disease was confirmed by confocal microscopy, after the mechanism of secondary angle closure was demonstrated by the UBM.
topic chandler's syndrome
confocal microscopy
iridocorneal endothelial cells
ultrasound biomicroscopy
url http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=528;epage=529;aulast=Ichhpujani
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AT amitgupta bilateralchandlerssyndromeuncommonentitydiagnosedbyultrasoundbiomicroscopyandconfocalmicroscopy
AT surinderspandav bilateralchandlerssyndromeuncommonentitydiagnosedbyultrasoundbiomicroscopyandconfocalmicroscopy
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