Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy
A 22‑year‑old female presented with bilateral, progressive diminution of vision. Slit‑lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad‑based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM),...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2020-01-01
|
Series: | Indian Journal of Ophthalmology |
Subjects: | |
Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=528;epage=529;aulast=Ichhpujani |
id |
doaj-fa919aa818b84e13bdc1656181dae762 |
---|---|
record_format |
Article |
spelling |
doaj-fa919aa818b84e13bdc1656181dae7622020-11-25T02:06:01ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892020-01-0168352852910.4103/ijo.IJO_1123_19Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopyParul IchhpujaniSushmita KaushikAmit GuptaSurinder S PandavA 22‑year‑old female presented with bilateral, progressive diminution of vision. Slit‑lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad‑based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM), a membrane extending from corneal endothelium to anterior iris surface causing traction was seen. Confocal microscopy showed an "epithelium‑like" transformation of the corneal endothelium. This case demonstrates a bilateral Chandler variant of the iridocorneal endothelial (ICE) syndrome where the diagnosis of Chandler′s disease was confirmed by confocal microscopy, after the mechanism of secondary angle closure was demonstrated by the UBM.http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=528;epage=529;aulast=Ichhpujanichandler's syndromeconfocal microscopyiridocorneal endothelial cellsultrasound biomicroscopy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Parul Ichhpujani Sushmita Kaushik Amit Gupta Surinder S Pandav |
spellingShingle |
Parul Ichhpujani Sushmita Kaushik Amit Gupta Surinder S Pandav Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy Indian Journal of Ophthalmology chandler's syndrome confocal microscopy iridocorneal endothelial cells ultrasound biomicroscopy |
author_facet |
Parul Ichhpujani Sushmita Kaushik Amit Gupta Surinder S Pandav |
author_sort |
Parul Ichhpujani |
title |
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy |
title_short |
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy |
title_full |
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy |
title_fullStr |
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy |
title_full_unstemmed |
Bilateral Chandler's syndrome: Uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy |
title_sort |
bilateral chandler's syndrome: uncommon entity diagnosed by ultrasound biomicroscopy and confocal microscopy |
publisher |
Wolters Kluwer Medknow Publications |
series |
Indian Journal of Ophthalmology |
issn |
0301-4738 1998-3689 |
publishDate |
2020-01-01 |
description |
A 22‑year‑old female presented with bilateral, progressive diminution of vision. Slit‑lamp examination revealed bilateral sectoral corneal edema. Gonioscopy showed broad‑based peripheral anterior synechiae and a membrane obscuring angle structure in both the eyes. On ultrasound biomicroscopy (UBM), a membrane extending from corneal endothelium to anterior iris surface causing traction was seen. Confocal microscopy showed an "epithelium‑like" transformation of the corneal endothelium. This case demonstrates a bilateral Chandler variant of the iridocorneal endothelial (ICE) syndrome where the diagnosis of Chandler′s disease was confirmed by confocal microscopy, after the mechanism of secondary angle closure was demonstrated by the UBM. |
topic |
chandler's syndrome confocal microscopy iridocorneal endothelial cells ultrasound biomicroscopy |
url |
http://www.ijo.in/article.asp?issn=0301-4738;year=2020;volume=68;issue=3;spage=528;epage=529;aulast=Ichhpujani |
work_keys_str_mv |
AT parulichhpujani bilateralchandlerssyndromeuncommonentitydiagnosedbyultrasoundbiomicroscopyandconfocalmicroscopy AT sushmitakaushik bilateralchandlerssyndromeuncommonentitydiagnosedbyultrasoundbiomicroscopyandconfocalmicroscopy AT amitgupta bilateralchandlerssyndromeuncommonentitydiagnosedbyultrasoundbiomicroscopyandconfocalmicroscopy AT surinderspandav bilateralchandlerssyndromeuncommonentitydiagnosedbyultrasoundbiomicroscopyandconfocalmicroscopy |
_version_ |
1724935506451496960 |