A Novel Live Attenuated Vaccine Candidate Protects Against Heterologous Senecavirus A Challenge

A Novel Live Attenuated Vaccine Candidate Protects Against Heterologous Senecavirus A Challenge

Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease (VD) clinically indistinguishable from foot-and-mouth disease (FMD) in pigs. Currently there are no vaccines currently available for SVA. Here we developed a recombinant SVA strain (rSVAm SacII) using reverse genetics and asse...

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Bibliographic Details
Main Authors: Bishwas Sharma, Maureen H. V. Fernandes, Marcelo de Lima, Lok R. Joshi, Steve Lawson, Diego G. Diel
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
Senecavirus A
Seneca Valley virus
recombinant virus
live attenuated vaccine
inactivated vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02660/full

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