siRNA-induced silencing of hypoxia-inducible factor 3α (HIF3α) increases endurance capacity in rats

siRNA-induced silencing of hypoxia-inducible factor 3α (HIF3α) increases endurance capacity in rats

Molecular mechanisms of adaptation to exercise despite a large number of studies remain unclear. One of the crucial factors in this process is hypoxia inducible factor (HIF) that regulates transcription of many target genes encoding proteins that are implicated in molecular adaptation to hypoxia. Ex...

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Bibliographic Details
Main Authors: S Drozdovska, B Gavenauskas, T Drevytska, V Nosar, V Nagibin, I Mankovska, V Dosenko
Format: Article
Language:English
Published: Termedia Publishing House 2016-04-01
Series:Biology of Sport
Subjects:
hypoxia-inducible factor 3α
endurance capacity
RNA interference
muscle
lung
heart
Online Access:http://www.termedia.pl/siRNA-induced-silencing-of-hypoxia-inducible-factor-3-HIF3-increases-endurance-capacity-in-rats,78,27429,1,1.html

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