ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia.

ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia.

Extracellular ATP is an important signaling molecule for vascular adaptation to limited oxygen availability (hypoxia). Here, we pursued the contribution of vascular endothelia to extracellular ATP release under hypoxic conditions.We gained first insight from studying ATP release from endothelia (HME...

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Bibliographic Details
Main Authors: Marion Faigle, Jessica Seessle, Stephanie Zug, Karim C El Kasmi, Holger K Eltzschig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2474679?pdf=render

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