DNA Damage Repair Status Predicts Opposite Clinical Prognosis Immunotherapy and Non-Immunotherapy in Hepatocellular Carcinoma

DNA Damage Repair Status Predicts Opposite Clinical Prognosis Immunotherapy and Non-Immunotherapy in Hepatocellular Carcinoma

Immune checkpoint inhibitors(ICIs) that activate tumor-specific immune responses bring new hope for the treatment of hepatocellular carcinoma(HCC). However, there are still some problems, such as uncertain curative effects and low objective response rates, which limit the curative effect of immunoth...

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Bibliographic Details
Main Authors: Yunfei Chen, Xu Wang, Xiaofan Deng, Yu Zhang, Rui Liao, Youzan Li, Hongji Yang, Kai Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Immune checkpoint inhibitors
hepatocellular carcinoma
DNA damage repair
tumor microenvironment
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676922/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.676922/full

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