Distinct requirements for the maintenance and establishment of mouse embryonic stem cells
Mouse embryonic stem cells (ESCs) that maintain a sustainable pluripotent state are derived from the inner cell mass (ICM) of blastocysts, in which pluripotency is lost during differentiation in vivo. It is unclear when and how the ability to maintain pluripotency is acquired during the derivation o...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-08-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506118301739 |