Distinct requirements for the maintenance and establishment of mouse embryonic stem cells

Mouse embryonic stem cells (ESCs) that maintain a sustainable pluripotent state are derived from the inner cell mass (ICM) of blastocysts, in which pluripotency is lost during differentiation in vivo. It is unclear when and how the ability to maintain pluripotency is acquired during the derivation o...

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Bibliographic Details
Main Authors: Riyo Konishi, Toru Nakano, Shinpei Yamaguchi
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118301739