Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patterns.

Expression profiling of FSHD-1 and FSHD-2 cells during myogenic differentiation evidences common and distinctive gene dysregulation patterns.

Determine global gene dysregulation affecting 4q-linked (FSHD-1) and non 4q-linked (FSHD-2) cells during early stages of myogenic differentiation. This approach has been never applied to FSHD pathogenesis.By in vitro differentiation of FSHD-1 and FSHD-2 myoblasts and gene chip analysis we derived th...

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Bibliographic Details
Main Authors: Stefania Cheli, Stephanie François, Beatrice Bodega, Francesco Ferrari, Elena Tenedini, Enrica Roncaglia, Sergio Ferrari, Enrico Ginelli, Raffaella Meneveri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3113851?pdf=render

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http://europepmc.org/articles/PMC3113851?pdf=render

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