Microwave-Assisted Synthesis, Proton Dissociation Processes, and Anticancer Evaluation of Novel D-Ring-Fused Steroidal 5-Amino-1-Arylpyrazoles

Microwave-Assisted Synthesis, Proton Dissociation Processes, and Anticancer Evaluation of Novel D-Ring-Fused Steroidal 5-Amino-1-Arylpyrazoles

Taking into account the pharmacological relevance of heterocycle-fused natural steroids, the objective of the current study was to develop a multistep reaction sequence for the efficient synthesis of novel D-ring-condensed 5-amino-1-arylpyrazoles from dehydroepiandrosterone (DHEA). A condensation re...

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Bibliographic Details
Main Authors: Gergő Mótyán, Ádám Baji, Małgorzata Anna Marć, Mohana Krishna Gopisetty, Dóra I. Adamecz, Mónika Kiricsi, Éva A. Enyedy, Éva Frank
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Applied Sciences
Subjects:
steroid
heterocycles
aminopyrazole
microwave
organic synthesis
proton dissociation
anticancer activity
Online Access:https://www.mdpi.com/2076-3417/10/1/229

Internet

https://www.mdpi.com/2076-3417/10/1/229

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