Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells.

Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells.

The outcome for patients with advanced metastatic and recurrent prostate cancer is still poor. Therefore, new chemotherapeutics are required, especially for killing cancer stem cells that are thought to be responsible for disease recurrence. In this study, we screened the effect of a novel palladium...

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Bibliographic Details
Main Authors: Engin Ulukaya, Fiona M Frame, Buse Cevatemre, Davide Pellacani, Hannah Walker, Vincent M Mann, Matthew S Simms, Michael J Stower, Veysel T Yilmaz, Norman J Maitland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3651166?pdf=render

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