Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.

Transketolase-like 1 expression is modulated during colorectal cancer progression and metastasis formation.

<h4>Background</h4>Transketolase-like 1 (TKTL1) induces glucose degradation through anaerobic pathways, even in presence of oxygen, favoring the malignant aerobic glycolytic phenotype characteristic of tumor cells. As TKTL1 appears to be a valid biomarker for cancer prognosis, the aim of...

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Bibliographic Details
Main Authors: Santiago Diaz-Moralli, Miriam Tarrado-Castellarnau, Cristina Alenda, Antoni Castells, Marta Cascante
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21980427/pdf/?tool=EBI

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