The role of transient receptor potential vanilloid type-2 (TRPV2) ion channels in innate and adaptive immune responses

The role of transient receptor potential vanilloid type-2 (TRPV2) ion channels in innate and adaptive immune responses

The Transient Receptor Potential Vanilloid type-2 (TRPV2), belonging to the TRP channel family, is a specialized ion channel expressed in human and other mammalian immune cells. This channel has been found to be expressed in CD34+ hematopoietic stem cells (HSCs), where its cytosolic Ca2+ activity is...

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Bibliographic Details
Main Authors: Giorgio eSantoni, Valerio eFarfariello, Sonia eLiberati, Maria Beatrice eMorelli, Massimo eNabissi, Matteo eSantoni, Consuelo eAmantini
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Immunology
Subjects:
Macrophages
B cell activation
T cell activation
Transient receptor potential; Transient receptor potential vanilloi type-2
Mastocytes
Immuno-mediated-diseases
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00034/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00034/full

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