The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice

The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice

<p>Abstract</p> <p>Background</p> <p>Skeletal muscle atrophy is a serious concern for the rehabilitation of patients afflicted by prolonged limb restriction. This debilitating condition is associated with a marked activation of NFκB activity. The ubiquitin-proteasome pa...

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Bibliographic Details
Main Authors: Trensz Frédéric, Leblanc Élisabeth, Haroun Sonia, Caron Annabelle Z, Guindi Chantal, Amrani Aziz, Grenier Guillaume
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Musculoskeletal Disorders
Online Access:http://www.biomedcentral.com/1471-2474/12/185

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