Mitigation of biases in estimating hazard ratios under non-sensitive and non-specific observation of outcomes–applications to influenza vaccine effectiveness
Abstract Background Non-sensitive and non-specific observation of outcomes in time-to-event data affects event counts as well as the risk sets, thus, biasing the estimation of hazard ratios. We investigate how imperfect observation of incident events affects the estimation of vaccine effectiveness b...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | Emerging Themes in Epidemiology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12982-020-00091-z |