Olfactory sensory activity modulates microglial-neuronal interactions during dopaminergic cell loss in the olfactory bulb

Olfactory sensory activity modulates microglial-neuronal interactions during dopaminergic cell loss in the olfactory bulb

The mammalian olfactory bulb (OB) displays robust activity-dependent plasticity throughout life. Dopaminergic (DA) neurons in the glomerular layer (GL) of the OB are particularly plastic, with loss of sensory input rapidly reducing tyrosine hydroxylase (TH) expression and dopamine production, follow...

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Bibliographic Details
Main Authors: Bryce Davis Grier, Leonardo Belluscio, Claire Elizabeth Jane Cheetham
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Microglia
plasticity
2-photon
dopaminergic neuron
olfactory
naris occlusion
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00178/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00178/full

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