Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes.

Recent proteome-wide screening approaches have provided a wealth of information about interacting proteins in various organisms. To test for a potential association between protein connectivity and the amount of predicted structural disorder, the disorder propensities of proteins with various number...

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Bibliographic Details
Main Authors: Chad Haynes, Christopher J Oldfield, Fei Ji, Niels Klitgord, Michael E Cusick, Predrag Radivojac, Vladimir N Uversky, Marc Vidal, Lilia M Iakoucheva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1526461?pdf=render