Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6

Klf4 Alleviates Lipopolysaccharide-Induced Inflammation by Inducing Expression of MCP-1 Induced Protein 1 to Deubiquitinate TRAF6

Background/Aims: Inflammation is an essential component of innate immunity against pathogens, but is tightly regulated, such as by Krüppel-like factor 4 (Klf4), to prevent injury. Klf4 also regulates macrophage polarization, although the mechanisms underlying both functions are poorly understood. Th...

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Bibliographic Details
Main Authors: Zhenzhen Li, Yanhui Jia, Shichao Han, Xingqin Wang, Fu Han, Julei Zhang, Wei Zhang, Hao Guan, Dahai Hu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Klf4
MCPIP1
Lipopolysaccharide
NF-κB
Deubiquitination
Online Access:https://www.karger.com/Article/FullText/491538

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