Correlation of Surgical Pleth Index with Stress Hormones during Propofol-Remifentanil Anaesthesia

Correlation of Surgical Pleth Index with Stress Hormones during Propofol-Remifentanil Anaesthesia

Eighty patients undergoing elective ear-nose-throat surgery were enrolled in the present study to investigate the relationship between surgical pleth index (SPI) and stress hormones (ACTH, cortisol, epinephrine, norepinephrine) during general anaesthesia which was induced and maintained with propofo...

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Bibliographic Details
Main Authors: Xinzhong Chen, Carsten Thee, Matthias Gruenewald, Christoph Ilies, Jan Höcker, Robert Hanss, Markus Steinfath, Berthold Bein
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/879158
Description
Summary:Eighty patients undergoing elective ear-nose-throat surgery were enrolled in the present study to investigate the relationship between surgical pleth index (SPI) and stress hormones (ACTH, cortisol, epinephrine, norepinephrine) during general anaesthesia which was induced and maintained with propofol and remifentanil using a target-controlled infusion. The study concluded that the SPI had moderate correlation to the stress hormones during general anaesthesia, but no correlation during consciousness. Furthermore, SPI values were able to predict ACTH values with high sensitivity and specificity.
ISSN:1537-744X

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