Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl.

Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl.

BACKGROUND: The dose-dependent toxicities of doxorubicin (DOX) limit its clinical applications, particularly in drug-resistant cancers, such as liver cancer. In this study, we investigated the role of quercetin on the antitumor effects of DOX on liver cancer cells and its ability to provide protecti...

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Bibliographic Details
Main Authors: Guanyu Wang, Jiawei Zhang, Luying Liu, Sherven Sharma, Qinghua Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519886?pdf=render

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