Fluid Shear Stress and Fibroblast Growth Factor-2 Increase Endothelial Cell-Associated Vitronectin

Vitronectin is a matricellular protein that plays an important role in both coagulation and angiogenesis through its effects on cell adhesion and the plasminogen system. Vitronectin is known to bind to endothelial cells upon integrin activation. However, the effect of integrin activation by shear st...

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Bibliographic Details
Main Authors: Justin G. Mathew, Sarah Basehore, Alisa Morss Clyne
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Applied Bionics and Biomechanics
Online Access:http://dx.doi.org/10.1155/2017/9040161