Comparison of dietary micronutrient intake in PCOS patients with and without metabolic syndrome

• Main Authors: Narges Zaeemzadeh, Shahideh Jahanian Sadatmahalleh, Saeideh Ziaei, Anoshirvan Kazemnejad, Maryam Movahedinejad, Azadeh Mottaghi, Neda Mohamadzadeh
• Format: Article
• Language: English
• Published: BMC 2021-01-01
• Series: Journal of Ovarian Research
• Subjects: Polycystic ovarian syndrome (PCOS); Metabolic syndrome (MetS); Antioxidants; Dietary intake; Micronutrients
• Online Access: https://doi.org/10.1186/s13048-020-00746-0

Abstract Background Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in reproductive-age women. It is one of the risk factors of metabolic syndrome (MetS). These two syndromes have an inflammatory etiologic foundation along with oxidative stress. The present study aimed to compare the dietary intake of antioxidant micronutrients in PCOS women with and without MetS. Materials and methods Overall, 42 participants eligible for this nested case control study were selected by the convenience sampling method. The case group included 14 PCOS patients with MetS and the control group included 28 PCOS patients without MetS. The dietary intake assessment of selenium, chromium, zinc, carotenoids, vitamin D and vitamin E was carried out by a 147-item Food Frequency Questionnaire (FFQ). PCOS and MetS were diagnosed using the Rotterdam criteria and NCEP ATP III, respectively. Statistical analysis was performed using SPSS16 software, T-test and Mann Whitney. Significant P-value was considered 0.05. Results Dietary intake of antioxidant micronutrients (selenium, zinc, chromium, carotenoids and vitamin E) was significantly lower in the PCOS women with MetS than in the control group (P < 0.05). Conclusion Since the PCOS patients without MetS had more intake of the aforementioned micronutrients than those with MetS, it is assumed that the dietary intake of these nutrients could probably have a protective effect on MetS.