The mammalian PYHIN gene family: Phylogeny, evolution and expression

The mammalian PYHIN gene family: Phylogeny, evolution and expression

<p>Abstract</p> <p>Background</p> <p>Proteins of the mammalian PYHIN (IFI200/HIN-200) family are involved in defence against infection through recognition of foreign DNA. The family member absent in melanoma 2 (AIM2) binds cytosolic DNA via its HIN domain and initiates...

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Bibliographic Details
Main Authors: Cridland Jasmyn A, Curley Eva Z, Wykes Michelle N, Schroder Kate, Sweet Matthew J, Roberts Tara L, Ragan Mark A, Kassahn Karin S, Stacey Katryn J
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Evolutionary Biology
Subjects:
PYHIN
HIN-200
cytosolic DNA
ALR
IFI16
AIM2
Online Access:http://www.biomedcentral.com/1471-2148/12/140

Internet

http://www.biomedcentral.com/1471-2148/12/140

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