Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment

Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment

Primary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor. Their morphology varies widely and includes teratoma, seminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, an...

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Main Authors: Lucian IORGA, Dragos MARCU, Ovidiu BRATU, Bogdan SOCEA, Tiberiu P. NEAGU, Simona BUNGAU, Ana Maria A. STANESCU, Camelia C. DIACONU, Dan MISCHIANU
Format: Article
Language:English
Published: Balkan Medical Union 2019-12-01
Series:Archives of the Balkan Medical Union
Subjects:
extragonadal germ-cell tumors
pathogenesis
histhopathology
diagnosis
treatment
Online Access:https://umbalk.org/wp-content/uploads/2019/11/16.EXTRAGONADAL-GERM%E2%80%91CELL-TUMORS.pdf
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spelling doaj-f99528b4e5d148b4984db245921d3b4c2020-11-25T02:38:24ZengBalkan Medical UnionArchives of the Balkan Medical Union1584-92442558-815X2019-12-01544 72573010.31688/ABMU.2019.54.4.16Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatmentLucian IORGADragos MARCU Ovidiu BRATUBogdan SOCEATiberiu P. NEAGUSimona BUNGAUAna Maria A. STANESCUCamelia C. DIACONUDan MISCHIANUPrimary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor. Their morphology varies widely and includes teratoma, seminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, and mixed GCTs. The ethiopathogenesis of EGCT is poorly understood, existing multiple theories. Diagnosis is often difficult, but an accurate one should be made in order to apply a correct management.https://umbalk.org/wp-content/uploads/2019/11/16.EXTRAGONADAL-GERM%E2%80%91CELL-TUMORS.pdfextragonadal germ-cell tumorspathogenesishisthopathologydiagnosistreatment
collection DOAJ
language English
format Article
sources DOAJ
author Lucian IORGA
Dragos MARCU
Ovidiu BRATU
Bogdan SOCEA
Tiberiu P. NEAGU
Simona BUNGAU
Ana Maria A. STANESCU
Camelia C. DIACONU
Dan MISCHIANU
spellingShingle Lucian IORGA
Dragos MARCU
Ovidiu BRATU
Bogdan SOCEA
Tiberiu P. NEAGU
Simona BUNGAU
Ana Maria A. STANESCU
Camelia C. DIACONU
Dan MISCHIANU
Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
Archives of the Balkan Medical Union
extragonadal germ-cell tumors
pathogenesis
histhopathology
diagnosis
treatment
author_facet Lucian IORGA
Dragos MARCU
Ovidiu BRATU
Bogdan SOCEA
Tiberiu P. NEAGU
Simona BUNGAU
Ana Maria A. STANESCU
Camelia C. DIACONU
Dan MISCHIANU
author_sort Lucian IORGA
title Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
title_short Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
title_full Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
title_fullStr Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
title_full_unstemmed Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
title_sort extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment
publisher Balkan Medical Union
series Archives of the Balkan Medical Union
issn 1584-9244
2558-815X
publishDate 2019-12-01
description Primary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor. Their morphology varies widely and includes teratoma, seminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, and mixed GCTs. The ethiopathogenesis of EGCT is poorly understood, existing multiple theories. Diagnosis is often difficult, but an accurate one should be made in order to apply a correct management.
topic extragonadal germ-cell tumors
pathogenesis
histhopathology
diagnosis
treatment
url https://umbalk.org/wp-content/uploads/2019/11/16.EXTRAGONADAL-GERM%E2%80%91CELL-TUMORS.pdf
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AT dragosmarcu extragonadalgermcelltumorsareviewofthepathogenesishistopathologicalfindingsdiagnosisandtreatment
AT ovidiubratu extragonadalgermcelltumorsareviewofthepathogenesishistopathologicalfindingsdiagnosisandtreatment
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