Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment

Extragonadal germ-cell tumors – a review of the pathogenesis, histopathological findings, diagnosis and treatment

Primary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor. Their morphology varies widely and includes teratoma, seminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, an...

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Bibliographic Details
Main Authors: Lucian IORGA, Dragos MARCU, Ovidiu BRATU, Bogdan SOCEA, Tiberiu P. NEAGU, Simona BUNGAU, Ana Maria A. STANESCU, Camelia C. DIACONU, Dan MISCHIANU
Format: Article
Language:English
Published: Balkan Medical Union 2019-12-01
Series:Archives of the Balkan Medical Union
Subjects:
extragonadal germ-cell tumors
pathogenesis
histhopathology
diagnosis
treatment
Online Access:https://umbalk.org/wp-content/uploads/2019/11/16.EXTRAGONADAL-GERM%E2%80%91CELL-TUMORS.pdf
Description
Summary:Primary extragonadal germ-cell tumors (EGCTs) are a rare group of neoplasms, that can exist anywere along the midline of the body, without the evidence of a primary gonadal tumor. Their morphology varies widely and includes teratoma, seminoma, yolk sac tumor, embryonal carcinoma, choriocarcinoma, and mixed GCTs. The ethiopathogenesis of EGCT is poorly understood, existing multiple theories. Diagnosis is often difficult, but an accurate one should be made in order to apply a correct management.
ISSN:1584-9244
2558-815X

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