KIAA0101 and UbcH10 interact to regulate non-small cell lung cancer cell proliferation by disrupting the function of the spindle assembly checkpoint

KIAA0101 and UbcH10 interact to regulate non-small cell lung cancer cell proliferation by disrupting the function of the spindle assembly checkpoint

Abstract Background Chromosome mis-segregation caused by spindle assembly checkpoint (SAC) dysfunction during mitosis is an important pathogenic factor in cancer, and modulating SAC function has emerged as a potential novel therapy for non-small cell lung cancer (NSCLC). UbcH10 is considered to be a...

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Bibliographic Details
Main Authors: Han Lei, Kun Wang, Tongying Jiang, Jingjing Lu, Xue Dong, Feilong Wang, Qiang Li, Liming Zhao
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
Non-small cell lung cancer
Spindle assembly checkpoint
UbcH10
KIAA0101
Online Access:http://link.springer.com/article/10.1186/s12885-020-07463-3

Internet

http://link.springer.com/article/10.1186/s12885-020-07463-3

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