Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations

Abstract The bright fluorescent cytosine analogue tCO stands out among fluorescent bases due to its virtually unquenched fluorescence emission in duplex DNA. However, like most reported base analogues, it has not been thoroughly characterized in RNA. We here report on the first synthesis and RNA-inc...

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Bibliographic Details
Main Authors: Anders Foller Füchtbauer, Søren Preus, Karl Börjesson, Scott A. McPhee, David M. J. Lilley, L. Marcus Wilhelmsson
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02453-1

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