High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome

High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome

<p>Abstract</p> <p>Background</p> <p>Neurotoxicity is a recognized complication of cyclosporine A (CSA) treatment. The incidence of severe CSA-related neurological complications following hematopoietic stem cell transplantation (HSCT) is 4-11%.</p> <p>Method...

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Main Authors: Minicucci Fabio, Vezzulli Paolo, Baldoli Cristina, Finizio Valentina, Biral Erika, Frugnoli Ilaria, Chiesa Robert, Biffi Alessandra, Cappelli Barbara, Noè Anna, Fanelli Giovanna, Fiori Rossana, Ciceri Fabio, Roncarolo Maria, Marktel Sarah
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Italian Journal of Pediatrics
Online Access:http://www.ijponline.net/content/36/1/14

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