Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development

It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing conserved network kernels stabilize evolutionary...

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Bibliographic Details
Main Authors: Gregory A. Cary, Brenna S. McCauley, Olga Zueva, Joseph Pattinato, William Longabaugh, Veronica F. Hinman
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20023-4