ADVANCED IN VIVO USE OF CRISPR/CAS9 AND ANTI-SENSE DNA INHIBITION FOR GENE MANIPULATION IN THE BRAIN

ADVANCED IN VIVO USE OF CRISPR/CAS9 AND ANTI-SENSE DNA INHIBITION FOR GENE MANIPULATION IN THE BRAIN

Gene-editing tools are essential for uncovering how genes mediate normal brain-behaviour relationships and contribute to neurodegenerative and neuropsychiatric disorders. Recent progress in gene-editing technology is now allowing neuroscientists unprecedented access to edit the genome efficiently. A...

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Bibliographic Details
Main Authors: Brandon J Walters, Amber B Azam, Colleen J Gillon, Sheena A Josselyn, Iva B Zovkic
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Genetics
Subjects:
Brain
CNS
Animal Models
knockdown
knockout
morpholino
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00362/full

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