Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine

Pseudoporphyria (PP) is a relatively rare, photodistributed bullous dermatosis that resembles porphyria cutanea tarda (PCT), but it is not accompanied by porphyrin abnormalities in the serum, urine, or stool. It was initially described in renal failure patients on dialysis. Thereafter, it has been...

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Main Authors: A. C. Katoulis, D. Ferra, E. Toumbis, E. Papadavid, A. Kanelleas, I. Panayiotides, D. Rigopoulos
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2013/271873
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spelling doaj-f9829cdc1ca344509ef54502d9a5e2cf2020-11-25T00:59:46ZengHindawi LimitedCase Reports in Dermatological Medicine2090-64632090-64712013-01-01201310.1155/2013/271873271873Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-AcetylcysteineA. C. Katoulis0D. Ferra1E. Toumbis2E. Papadavid3A. Kanelleas4I. Panayiotides5D. Rigopoulos6Second Department of Dermatology, “Attikon” General University Hospital, University of Athens, 1 Rimini Street, 124 62 Chaidari, GreeceSecond Department of Dermatology, “Attikon” General University Hospital, University of Athens, 1 Rimini Street, 124 62 Chaidari, GreeceSecond Department of Dermatology, “Attikon” General University Hospital, University of Athens, 1 Rimini Street, 124 62 Chaidari, GreeceSecond Department of Dermatology, “Attikon” General University Hospital, University of Athens, 1 Rimini Street, 124 62 Chaidari, GreeceSecond Department of Dermatology, “Attikon” General University Hospital, University of Athens, 1 Rimini Street, 124 62 Chaidari, GreeceHistopathology Department, “Attikon” General University Hospital, University of Athens, 124 62 Chaidari, GreeceSecond Department of Dermatology, “Attikon” General University Hospital, University of Athens, 1 Rimini Street, 124 62 Chaidari, GreecePseudoporphyria (PP) is a relatively rare, photodistributed bullous dermatosis that resembles porphyria cutanea tarda (PCT), but it is not accompanied by porphyrin abnormalities in the serum, urine, or stool. It was initially described in renal failure patients on dialysis. Thereafter, it has been associated with several aetiological factors. We report a case of PP in a 67-year-old woman with mild renal failure, successfully treated with N-acetylcysteine. This is the second reported case of PP developing in nondialyzed chronic renal failure. Such cases support the view that renal impairment itself may play a more important aetiological role in developing PP than it was originally considered.http://dx.doi.org/10.1155/2013/271873
collection DOAJ
language English
format Article
sources DOAJ
author A. C. Katoulis
D. Ferra
E. Toumbis
E. Papadavid
A. Kanelleas
I. Panayiotides
D. Rigopoulos
spellingShingle A. C. Katoulis
D. Ferra
E. Toumbis
E. Papadavid
A. Kanelleas
I. Panayiotides
D. Rigopoulos
Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine
Case Reports in Dermatological Medicine
author_facet A. C. Katoulis
D. Ferra
E. Toumbis
E. Papadavid
A. Kanelleas
I. Panayiotides
D. Rigopoulos
author_sort A. C. Katoulis
title Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine
title_short Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine
title_full Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine
title_fullStr Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine
title_full_unstemmed Pseudoporphyria Associated with Nonhemodialyzed Renal Insufficiency, Successfully Treated with Oral N-Acetylcysteine
title_sort pseudoporphyria associated with nonhemodialyzed renal insufficiency, successfully treated with oral n-acetylcysteine
publisher Hindawi Limited
series Case Reports in Dermatological Medicine
issn 2090-6463
2090-6471
publishDate 2013-01-01
description Pseudoporphyria (PP) is a relatively rare, photodistributed bullous dermatosis that resembles porphyria cutanea tarda (PCT), but it is not accompanied by porphyrin abnormalities in the serum, urine, or stool. It was initially described in renal failure patients on dialysis. Thereafter, it has been associated with several aetiological factors. We report a case of PP in a 67-year-old woman with mild renal failure, successfully treated with N-acetylcysteine. This is the second reported case of PP developing in nondialyzed chronic renal failure. Such cases support the view that renal impairment itself may play a more important aetiological role in developing PP than it was originally considered.
url http://dx.doi.org/10.1155/2013/271873
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