Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples.

Using long ssDNA polynucleotides to amplify STRs loci in degraded DNA samples.

Obtaining informative short tandem repeat (STR) profiles from degraded DNA samples is a challenging task usually undermined by locus or allele dropouts and peak-high imbalances observed in capillary electrophoresis (CE) electropherograms, especially for those markers with large amplicon sizes. We he...

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Bibliographic Details
Main Authors: Martín E Mautner, Agustín Pérez Santángelo, Rodrigo M Corti Bielsa, Andrea Sala, Santiago Ginart, Daniel Corach
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5669423?pdf=render

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http://europepmc.org/articles/PMC5669423?pdf=render

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