A thermodynamically consistent model of the post-translational Kai circadian clock.

A thermodynamically consistent model of the post-translational Kai circadian clock.

The principal pacemaker of the circadian clock of the cyanobacterium S. elongatus is a protein phosphorylation cycle consisting of three proteins, KaiA, KaiB and KaiC. KaiC forms a homohexamer, with each monomer consisting of two domains, CI and CII. Both domains can bind and hydrolyze ATP, but only...

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Bibliographic Details
Main Authors: Joris Paijmans, David K Lubensky, Pieter Rein Ten Wolde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5371392?pdf=render

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