Transmitters and pathways mediating inhibition of spinal itch-signaling neurons by scratching and other counterstimuli.

Transmitters and pathways mediating inhibition of spinal itch-signaling neurons by scratching and other counterstimuli.

Scratching relieves itch, but the underlying neural mechanisms are poorly understood. We presently investigated a role for the inhibitory neurotransmitters GABA and glycine in scratch-evoked inhibition of spinal itch-signaling neurons in a mouse model of chronic dry skin itch. Superficial dorsal hor...

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Bibliographic Details
Main Authors: Tasuku Akiyama, Mirela Iodi Carstens, Earl Carstens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3144926?pdf=render

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