Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting

Screening of Transcription Factors Involved in Fetal Hemoglobin Regulation Using Phylogenetic Footprinting

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Fetal hemoglobin (Hb F) is an important genetic modulator of the beta-hemoglobinopathies. The regulation of Hb F levels is influenced by transcription factors. We used phylogenetic footprinting to screen transcription factors that have binding sites in HBG1 and HBG2 genes’ noncoding regions in order...

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Bibliographic Details
Main Authors: Gisele Cristine De Souza Carrocini, Larissa Paola Rodrigues Venancio, Claudia Regina Bonini-Domingos
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Evolutionary Bioinformatics
Online Access:https://doi.org/10.4137/EBO.S15364

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