SARS‐CoV‐2 worldwide replication drives rapid rise and selection of mutations across the viral genome: a time‐course study – potential challenge for vaccines and therapies

SARS‐CoV‐2 worldwide replication drives rapid rise and selection of mutations across the viral genome: a time‐course study – potential challenge for vaccines and therapies

Abstract Scientists and the public were alarmed at the first large viral variant of SARS‐CoV‐2 reported in December 2020. We have followed the time course of emerging viral mutants and variants during the SARS‐CoV‐2 pandemic in ten countries on four continents. We examined > 383,500 complete SARS...

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Bibliographic Details
Main Authors: Stefanie Weber, Christina M Ramirez, Barbara Weiser, Harold Burger, Walter Doerfler
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:EMBO Molecular Medicine
Subjects:
high incidence of C to T transitions
numerous new mutations
South African and Brazil variants
time course of SARS‐CoV‐2 mutant emergence
UK variant B.1.1.7
Online Access:https://doi.org/10.15252/emmm.202114062

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