Advances in Human Immune System Mouse Models for Personalized Treg-Based Immunotherapies

Advances in Human Immune System Mouse Models for Personalized Treg-Based Immunotherapies

Immunodeficient mice engrafted with a functional human immune system [Human immune system (HIS) mice] have paved the way to major advances for personalized medicine and translation of immune-based therapies. One prerequisite for advancing personalized medicine is modeling the immune system of indivi...

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Bibliographic Details
Main Authors: Isabelle Serr, Maria Kral, Martin G. Scherm, Carolin Daniel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
HIS mice
Treg
cancer immunotherapy
personalized medicine
iPSC-derived HSCs
microRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643544/full

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