Iron Oxide Nanoparticle Uptake in Mouse Brachiocephalic Artery Atherosclerotic Plaque Quantified by T<sub>2</sub>-Mapping MRI

Iron Oxide Nanoparticle Uptake in Mouse Brachiocephalic Artery Atherosclerotic Plaque Quantified by T<sub>2</sub>-Mapping MRI

The purpose of our study was to monitor the iron oxide contrast agent uptake in mouse brachiocephalic artery (BCA) atherosclerotic plaques in vivo by quantitative T<sub>2</sub>-mapping magnetic resonance imaging (MRI). Female ApoE-/- mice (<i>n</i> = 32) on a 15-week Western-...

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Bibliographic Details
Main Authors: Rik P.M. Moonen, Bram F. Coolen, Judith C. Sluimer, Mat J.A.P. Daemen, Gustav J. Strijkers
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
T<sub>2</sub> mapping
quantitative MRI
USPIO
atherosclerosis
inflammation
macrophages
Online Access:https://www.mdpi.com/1999-4923/13/2/279

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https://www.mdpi.com/1999-4923/13/2/279

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