Simvastatin enhances proliferation and pluripotent gene expression by canine bone marrow-derived mesenchymal stem cells (cBM-MSCs) in vitro

Simvastatin enhances proliferation and pluripotent gene expression by canine bone marrow-derived mesenchymal stem cells (cBM-MSCs) in vitro

Establishing the intervention to enhance proliferation and differentiation potential is crucial for the clinical translation of stem cell-based therapy. In this study, the effects of simvastatin on these regards were explored. Canine bone marrow-derived mesenchymal stem cells (cBM-MSCs) were treated...

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Bibliographic Details
Main Authors: Sirirat Nantavisai, Watchareewan Rodprasert, Koranis Pathanachai, Parattakorn Wikran, Podchana Kitcharoenthaworn, Saritpakorn Smithiwong, Suyakarn Archasappawat, Chenphop Sawangmake
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Heliyon
Subjects:
Cell biology
Cell culture
Cell death
Cytotoxicity
Stem cell research
Regenerative medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019363236

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