The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu
<p>Abstract</p> <p>Background</p> <p>The Human Immunodeficiency virus type 1 (HIV-1) Vpu protein enhances virus release from infected cells and induces proteasomal degradation of CD4. Recent work identified BST-2/CD317 as a host factor that inhibits HIV-1 virus release...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-09-01
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Series: | Retrovirology |
Online Access: | http://www.retrovirology.com/content/6/1/80 |