Cytochemical and mycrobicide activity of blood phagocytes in pulmonary tuberculosis patients

• Main Authors: O. V. Filinyuk, N. A. Zemlyanaya, A. K. Strelis, O. I. Ourazova, O. V. Voronkova, N. M. Shevtsova, I. Ye. Yesimova
• Format: Article
• Language: English
• Published: Siberian State Medical University (Tomsk) 2007-03-01
• Series: Bûlleten' Sibirskoj Mediciny
• Subjects: pulmonary tuberculosis; neutrophils; monocytes; phagocytosis
• Online Access: https://bulletin.tomsk.ru/jour/article/view/3221

Aimed at non-specific reactivity of the organism, cytochemical activity and microbicidal properties of blood neutrophils and peripheral blood monocytes were studied in 102 patients with drug-sensitive pulmonary tuberculosis before the treatment, after in-tensive phase of therapy and after stopping anti-tuberculosis therapy. Increased hydrolytic enzymes' activity of leucocytes, levels of non- cationic proteins and decreased levels of cellular glycogen and induced NBT-test were observed without their dependence on drug-sensitivity of mycobacterial tuberculosis before and during the treatment.. At the same time, content of lipids in neutrophils and monocytes undergoes different changes.