Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report

Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of car...

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Main Authors: Angela Basnet, Shiva Kumar Ojha, Suman Kumar Jha, Anjana Paudyal, Manoj Khadka, Manita Khadka, Dhan Bahadur Shrestha
Format: Article
Language:English
Published: Nepal Medical Association 2021-08-01
Series:Journal of Nepal Medical Association
Subjects:
Online Access:https://www.jnma.com.np/jnma/index.php/jnma/article/view/6454
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spelling doaj-f9397936c97e4142b17ef002f5eb1bd62021-08-14T18:29:13ZengNepal Medical AssociationJournal of Nepal Medical Association0028-27151815-672X2021-08-015924010.31729/jnma.6454Cardiovascular Complication following Covishield Vaccination in Nepal: A Case ReportAngela Basnet0Shiva Kumar Ojha1Suman Kumar Jha2Anjana Paudyal3Manoj Khadka4Manita Khadka5Dhan Bahadur Shrestha6Department of Internal Medicine, Scheer Memorial Adventist Hospital, Banepa, Kavrepalanchok, NepalDepartment of Internal Medicine, Scheer Memorial Adventist Hospital, Banepa, Kavrepalanchok, NepalDepartment of Internal Medicine, Scheer Memorial Adventist Hospital, Banepa, Kavrepalanchok, NepalDepartment of Internal Medicine, Scheer Memorial Adventist Hospital, Banepa, Kavrepalanchok, NepalNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, NepalNepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, NepalDepartment of Internal Medicine, Mount Sinai Hospital, Chicago, USA Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of cardiovascular complication following Covishield vaccination in a 33 years old female who had dizziness and elevated blood pressure immediately following vaccination and abnormal electrocardiogram showing T wave inversions followed by left bundle branch block. The patient was kept on observation, following which the blood pressure and electrocardiogram changes were normal by seven days. This cardiovascular complication following the vaccination demands further investigation into the adverse event of the vaccine. However, since the benefit of the vaccine outweighs the risk, World Health Organization has recommended the continuity of the vaccine as of now. https://www.jnma.com.np/jnma/index.php/jnma/article/view/6454bundle-branch block; case report; COVID-19 vaccine; Nepal.
collection DOAJ
language English
format Article
sources DOAJ
author Angela Basnet
Shiva Kumar Ojha
Suman Kumar Jha
Anjana Paudyal
Manoj Khadka
Manita Khadka
Dhan Bahadur Shrestha
spellingShingle Angela Basnet
Shiva Kumar Ojha
Suman Kumar Jha
Anjana Paudyal
Manoj Khadka
Manita Khadka
Dhan Bahadur Shrestha
Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
Journal of Nepal Medical Association
bundle-branch block; case report; COVID-19 vaccine; Nepal.
author_facet Angela Basnet
Shiva Kumar Ojha
Suman Kumar Jha
Anjana Paudyal
Manoj Khadka
Manita Khadka
Dhan Bahadur Shrestha
author_sort Angela Basnet
title Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_short Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_full Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_fullStr Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_full_unstemmed Cardiovascular Complication following Covishield Vaccination in Nepal: A Case Report
title_sort cardiovascular complication following covishield vaccination in nepal: a case report
publisher Nepal Medical Association
series Journal of Nepal Medical Association
issn 0028-2715
1815-672X
publishDate 2021-08-01
description Nepal started the COVID-19 vaccination on 27 January 2021 with AstraZeneca/Oxford Coronavirus Disease-19 AZD1222 (Covishield) vaccine to control the Coronavirus disease pandemic. The vaccine has a good safety profile, with cardiovascular complications being rare. Herein we report a rare case of cardiovascular complication following Covishield vaccination in a 33 years old female who had dizziness and elevated blood pressure immediately following vaccination and abnormal electrocardiogram showing T wave inversions followed by left bundle branch block. The patient was kept on observation, following which the blood pressure and electrocardiogram changes were normal by seven days. This cardiovascular complication following the vaccination demands further investigation into the adverse event of the vaccine. However, since the benefit of the vaccine outweighs the risk, World Health Organization has recommended the continuity of the vaccine as of now.
topic bundle-branch block; case report; COVID-19 vaccine; Nepal.
url https://www.jnma.com.np/jnma/index.php/jnma/article/view/6454
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