TANK Promotes Pressure Overload Induced Cardiac Hypertrophy via Activating AKT Signaling Pathway

TANK Promotes Pressure Overload Induced Cardiac Hypertrophy via Activating AKT Signaling Pathway

Background: TANK (TRAF family member associated NF-κB activator) acts as a member of scaffold proteins participated in the development of multiple diseases. However, its function in process of cardiac hypertrophy is still unknown.Methods and Results: In this study, we observed an increased expressio...

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Bibliographic Details
Main Authors: Yanan Pang, Minglu Ma, Dong Wang, Xun Li, Li Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
TRAF family member associated NF-κB activator
AKT signal pathway
scaffold protein
pathological cardiac hypertrophy
tansgenic mice
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.687540/full

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