High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing.

High resolution size analysis of fetal DNA in the urine of pregnant women by paired-end massively parallel sequencing.

BACKGROUND: Fetal DNA in maternal urine, if present, would be a valuable source of fetal genetic material for noninvasive prenatal diagnosis. However, the existence of fetal DNA in maternal urine has remained controversial. The issue is due to the lack of appropriate technology to robustly detect th...

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Bibliographic Details
Main Authors: Nancy B Y Tsui, Peiyong Jiang, Katherine C K Chow, Xiaoxi Su, Tak Y Leung, Hao Sun, K C Allen Chan, Rossa W K Chiu, Y M Dennis Lo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3485143?pdf=render

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