Discrimination of DNA Methylation Signal from Background Variation for Clinical Diagnostics

Discrimination of DNA Methylation Signal from Background Variation for Clinical Diagnostics

Advances in the study of human DNA methylation variation offer a new avenue for the translation of epigenetic research results to clinical applications. Although current approaches to methylome analysis have been helpful in revealing an epigenetic influence in major human diseases, this type of anal...

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Bibliographic Details
Main Authors: Robersy Sanchez, Xiaodong Yang, Thomas Maher, Sally A. Mackenzie
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
dna methylation
signal detection
machine learning
leukemia
autism
clinical diagnostic
Online Access:https://www.mdpi.com/1422-0067/20/21/5343

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