Identification of Residues in Lassa Virus Glycoprotein Subunit 2 That Are Critical for Protein Function

Identification of Residues in Lassa Virus Glycoprotein Subunit 2 That Are Critical for Protein Function

Lassa virus (LASV) is an Old World arenavirus, endemic to West Africa, capable of causing hemorrhagic fever. Currently, there are no approved vaccines or effective antivirals for LASV. However, thorough understanding of the LASV glycoprotein and entry into host cells could accelerate therapeutic des...

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Bibliographic Details
Main Authors: Katherine A. Willard, Jacob T. Alston, Marissa Acciani, Melinda A. Brindley
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Pathogens
Subjects:
Lassa virus
arenavirus
viral glycoprotein
viral entry
viral fusion
fusion protein
Online Access:http://www.mdpi.com/2076-0817/8/1/1

Internet

http://www.mdpi.com/2076-0817/8/1/1

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